General Chemistry


Publications
57

The protein interactome of the citrus Huanglongbing pathogen Candidatus Liberibacter asiaticus

Citation
Carter et al. (2023). Nature Communications 14 (1)
Names
Ca. Liberibacter asiaticus
Abstract
AbstractThe bacterium Candidatus Liberibacter asiaticus (CLas) causes citrus Huanglongbing disease. Our understanding of the pathogenicity and biology of this microorganism remains limited because CLas has not yet been cultivated in artificial media. Its genome is relatively small and encodes approximately 1136 proteins, of which 415 have unknown functions. Here, we use a high-throughput yeast-two-hybrid (Y2H) screen to identify interactions between CLas proteins, thus providing insights into th

Globally distributed Myxococcota with photosynthesis gene clusters illuminate the origin and evolution of a potentially chimeric lifestyle

Citation
Li et al. (2023). Nature Communications 14 (1)
Names
“Houyibacterium oceanica” “Houyibacterium” “Houyibacteriaceae” “Houyihalomonas phototrophica” “Xihehalomonas phototrophica” “Xihemonas sinensis” “Kuafubacteria” “Kuafubacterium phototrophica” “Kuafucaenimonas phototrophica” “Kuafuhalomonas phototrophica” “Xihepedomonas phototrophica” “Xihelimnomonas phototrophica” “Xihecaenimonas phototrophica” “Kuafubacteriales” “Kuafubacteriaceae” “Xihehalomonas” “Xihemonas” “Xihecaenibacterium” “Houyihalomonas” “Xihelimnobacterium phototrophica” “Xihelimnobacterium” “Xihemonas phototrophica” “Xihecaenibacterium phototrophica” “Xihebacterium phototrophica” “Xihebacterium glacialis” “Xihebacterium aquatica” “Xihemicrobium phototrophica” “Xihemicrobium aquatica” “Kuafubacterium” “Xihebacterium” “Xihemicrobium” “Xihecaenimonas” “Xihelimnomonas” “Xihepedomonas” “Kuafuhalomonas” “Kuafucaenimonas”
Abstract
AbstractPhotosynthesis is a fundamental biogeochemical process, thought to be restricted to a few bacterial and eukaryotic phyla. However, understanding the origin and evolution of phototrophic organisms can be impeded and biased by the difficulties of cultivation. Here, we analyzed metagenomic datasets and found potential photosynthetic abilities encoded in the genomes of uncultivated bacteria within the phylum Myxococcota. A putative photosynthesis gene cluster encoding a type-II reaction cent

Multi-heme cytochrome-mediated extracellular electron transfer by the anaerobic methanotroph ‘Candidatus Methanoperedens nitroreducens’

Citation
Zhang et al. (2023). Nature Communications 14 (1)
Names
Ca. Methanoperedens nitroreducens
Abstract
AbstractAnaerobic methanotrophic archaea (ANME) carry out anaerobic oxidation of methane, thus playing a crucial role in the methane cycle. Previous genomic evidence indicates that multi-heme c-type cytochromes (MHCs) may facilitate the extracellular electron transfer (EET) from ANME to different electron sinks. Here, we provide experimental evidence supporting cytochrome-mediated EET for the reduction of metals and electrodes by ‘Candidatus Methanoperedens nitroreducens’, an ANME acclimated to

Ecophysiology and interactions of a taurine-respiring bacterium in the mouse gut

Citation
Ye et al. (2023). Nature Communications 14 (1)
Names
Taurinivorans muris Ts Taurinivorans
Abstract
AbstractTaurine-respiring gut bacteria produce H2S with ambivalent impact on host health. We report the isolation and ecophysiological characterization of a taurine-respiring mouse gut bacterium. Taurinivorans muris strain LT0009 represents a new widespread species that differs from the human gut sulfidogen Bilophila wadsworthia in its sulfur metabolism pathways and host distribution. T. muris specializes in taurine respiration in vivo, seemingly unaffected by mouse diet and genotype, but is dep

New globally distributed bacterial phyla within the FCB superphylum

Citation
Gong et al. (2022). Nature Communications 13 (1)
Names
“Orphanbacterum longqiense” “Joyebacterota” “Arandabacteraceae” “Arandabacterota” “Arandabacterales” “Arandabacteria” “Orphanbacterum” “Arandabacterum bohaiense” “Blakebacterota” “Orphanbacteraceae” “Joyebacterum haimaense” “Blakebacterum guaymasense” “Orphanbacterales” “Joyebacterum” “Blakebacterum” “Orphanbacteria” “Joyebacteraceae” “Blakebacteraceae” “Orphanbacterota” “Joyebacterales” “Blakebacterales” “Arandabacterum” “Joyebacteria” “Blakebacteria”
Abstract
AbstractMicrobes in marine sediments play crucial roles in global carbon and nutrient cycling. However, our understanding of microbial diversity and physiology on the ocean floor is limited. Here, we use phylogenomic analyses of thousands of metagenome-assembled genomes (MAGs) from coastal and deep-sea sediments to identify 55 MAGs that are phylogenetically distinct from previously described bacterial phyla. We propose that these MAGs belong to 4 novel bacterial phyla (Blakebacterota, Orphanbact

An essential role for tungsten in the ecology and evolution of a previously uncultivated lineage of anaerobic, thermophilic Archaea

Citation
Buessecker et al. (2022). Nature Communications 13 (1)
Names
Wolframiiraptor gerlachensis Ts Wolframiiraptor Wolframiiraptoraceae Benthortus lauensis Ts Geocrenenecus dongiae Ts Geocrenenecus arthurdayi Geocrenenecus huangii Terraquivivens ruidianensis Terraquivivens tengchongensis Terraquivivens yellowstonensis Benthortus Geocrenenecus Terraquivivens Terraquivivens tikiterensis Ts Wolframiiraptor sinensis Wolframiiraptor allenii
Abstract
AbstractTrace metals have been an important ingredient for life throughout Earth’s history. Here, we describe the genome-guided cultivation of a member of the elusive archaeal lineage Caldarchaeales (syn. Aigarchaeota), Wolframiiraptor gerlachensis, and its growth dependence on tungsten. A metagenome-assembled genome (MAG) of W. gerlachensis encodes putative tungsten membrane transport systems, as well as pathways for anaerobic oxidation of sugars probably mediated by tungsten-dependent ferredox