General Medicine


Publications (509)

Ciclo biológico de Bactericera cockerelli, vector de la enfermedad de punta morada (Candidatus liberobacter) en solanáceas, en los andes centrales ecuatorianos

Citation
Jácome - Mogro et al. (2022). Revista Investigación Agraria 4 (1)
Subjects
General Medicine
Abstract
El trabajo se llevó a cabo en tres localidades, Salache, Machachi y Saquisilí, donde se determinó el comportamiento y hábitos del psílido (Bactericera cockerelli.), responsable de la transmisión del fitoplasma conocido como punta morada en el cultivo de papa (Solanum tuberosum). Se observó el desarrollo del insecto, alimentándolo con follaje fresco de plantas de papa, mantenidos en cámaras artesanales de cría; para Salache la temperatura promedio fue de 21 ºC y una humedad relativa del 68% con un ciclo total de 31 días; para Saquisilí se mantuvieron con una humedad relativa promedio de 75%, y una temperatura de 13,9°C con un ciclo total de 33 días y en Machachi se mantuvo una temperatura alrededor de 17°C y una humedad relativa de 74% con un ciclo total de 34 días.  Los datos registrados en todo el proceso fueron: número de huevos depositados, tiempo de desarrollo de cada estado ninfal y duración de la etapa adulto. Las observaciones se realizaron durante los meses de octubre, noviembre y diciembre, en donde se registraron los datos de los primeros instares de B. cockerelli hasta su última etapa, logrando determinar que la localidad Saquisilí tuvo un desarrollo oval rápido promedio de 2 a 6 días y la localidad más longeva en etapa adulta de B. cockerelli fue Salache, la misma que además obtuvo el mejor desarrollo en el ciclo biológico total de la especie.   

Amycolatopsis camponoti sp. nov., new tetracenomycin-producing actinomycete isolated from carpenter ant Camponotus vagus

Citation
Zakalyukina et al. (2022). Antonie van Leeuwenhoek 115 (4)
Names (1)
Amycolatopsis camponoti
Subjects
General Medicine Microbiology Molecular Biology
Abstract
AbstractAn actinobacterial strain A23T, isolated from adult ant Camponotus vagus collected in Ryazan region (Russia) and established as tetracenomycin X producer, was subjected to a polyphasic taxonomic study. Morphological characteristics of this strain included well-branched substrate mycelium and aerial hyphae fragmented into rod-shaped elements. Phylogenetic analyses based on 16S rRNA gene and genome sequences showed that strain A23T was most closely related to Amycolatopsis pretoriensis DSM 44654T. Average nucleotide identity and digital DNA–DNA hybridization values between the genome sequences of isolate A23T and its closest relative, Amycolatopsis pretoriensis DSM 44654T, were 39.5% and 88.6%, which were below the 70% and 95–96% cut-off point recommended for bacterial species demarcation, respectively. The genome size of the isolate A23T was 10,560,374 bp with a DNA G + C content of 71.2%. The whole-cell hydrolysate contained meso-diaminopimelic acid and arabinose and galactose as main diagnostic sugars as well as ribose and rhamnose. It contained MK-9(H4) as the predominant menaquinone and iso-C16:0, iso-C15:0, anteiso-C17:0 and C16:0 as the major cellular fatty acids. Diphosphatidylglycerol and phosphatidylethanolamine prevailed among phospholipids. Mycolic acids were not detected. Based on the phenotypic, genomic and phylogenetic data, isolate A23T represents a novel species of the genus Amycolatopsis, for which the name Amycolatopsis camponoti sp. nov. is proposed, and the type strain is A23T (= DSM 111725T = VKM Ac-2882T).

The Longitudinal Dividing Bacterium Candidatus Thiosymbion Oneisti Has a Natural Temperature-Sensitive FtsZ Protein with Low GTPase Activity

Citation
Wang et al. (2022). International Journal of Molecular Sciences 23 (6)
Names (2)
Ca. Thiosymbion oneisti Ca. Thiosymbion
Subjects
Catalysis Computer Science Applications General Medicine Inorganic Chemistry Molecular Biology Organic Chemistry Physical and Theoretical Chemistry Spectroscopy
Abstract
FtsZ, the bacterial tubulin-homolog, plays a central role in cell division and polymerizes into a ring-like structure at midcell to coordinate other cell division proteins. The rod-shaped gamma-proteobacterium Candidatus Thiosymbion oneisti has a medial discontinuous ellipsoidal “Z-ring.” Ca. T. oneisti FtsZ shows temperature-sensitive characteristics when it is expressed in Escherichia coli, where it localizes at midcell. The overexpression of Ca. T. oneisti FtsZ interferes with cell division and results in filamentous cells. In addition, it forms ring- and barrel-like structures independently of E. coli FtsZ, which suggests that the difference in shape and size of the Ca. T. oneisti FtsZ ring is likely the result of its interaction with Z-ring organizing proteins. Similar to some temperature-sensitive alleles of E. coli FtsZ, Ca. T. oneisti FtsZ has a weak GTPase and does not polymerize in vitro. The temperature sensitivity of Ca. Thiosymbion oneisti FtsZ is likely an adaptation to the preferred temperature of less than 30 °C of its host, the nematode Laxus oneistus.

Not Just a Cycle: Three gab Genes Enable the Non-Cyclic Flux Toward Succinate via GABA Shunt in ‘Candidatus Liberibacter asiaticus’–Infected Citrus

Citation
Nehela, Killiny (2022). Molecular Plant-Microbe Interactions® 35 (3)
Names (1)
Ca. Liberibacter asiaticus
Subjects
Agronomy and Crop Science General Medicine Physiology
Abstract
Although the mitochondria retain all required enzymes for an intact tricarboxylic acid (TCA) cycle, plants might shift the cyclic flux from the TCA cycle to an alternative noncyclic pathway via γ-aminobutyric acid (GABA) shunt under specific physiological conditions. We hypothesize that several genes may ease this noncyclic flux and contribute to the citrus response to the phytopathogenic bacterium ‘Candidatus Liberibacter asiaticus’, the causal agent of Huanglongbing in citrus. To test this hypothesis, we used multiomics techniques (metabolomics, fluxomics, and transcriptomics) to investigate the potential roles of putative gab homologies from Valencia sweet orange (Citrus sinensis). Our findings showed that ‘Ca. L. asiaticus’ significantly increased the endogenous GABA and succinate content but decreased ketoglutarate in infected citrus plants. Citrus genome harbors three putative gab genes, including amino-acid permease (also known as GABA permease; CsgabP), GABA transaminase (CsgabT), and succinate-semialdehyde dehydrogenase (also known as GABA dehydrogenase; CsgabD). The transcript levels of CsgabP, CsgabT, and CsgabD were upregulated in citrus leaves upon the infection with ‘Ca. L. asiaticus’ and after the exogenous application of GABA or deuterium-labeled GABA isotope (GABA-D6). Moreover, our finding showed that exogenously applied GABA is quickly converted to succinate and fed into the TCA cycle. Likewise, the fluxomics study showed that GABA-D6 is rapidly metabolized to succinate-D4. Our work proved that GABA shunt and three predicated gab genes from citrus, support the upstream noncyclic flux toward succinate rather than an intact TCA cycle and contribute to citrus defense responses to ‘Ca. L. asiaticus’. [Formula: see text] Copyright © 2022 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license .

Candidatus Liberibacter asiaticus’-Encoded BCP Peroxiredoxin Suppresses Lipopolysaccharide-Mediated Defense Signaling and Nitrosative Stress In Planta

Citation
Jain et al. (2022). Molecular Plant-Microbe Interactions® 35 (3)
Names (2)
Ca. Liberibacter asiaticus Liberibacter
Subjects
Agronomy and Crop Science General Medicine Physiology
Abstract
The lipopolysaccharides (LPS) of gram-negative bacteria trigger a nitrosative and oxidative burst in both animals and plants during pathogen invasion. Liberibacter crescens strain BT-1 is a surrogate for functional genomic studies of the uncultured pathogenic ‘Candidatus Liberibacter’ spp. that are associated with severe diseases such as citrus greening and potato zebra chip. Structural determination of L. crescens LPS revealed the presence of a very long chain fatty acid modification. L. crescens LPS pretreatment suppressed growth of Xanthomonas perforans on nonhost tobacco (Nicotiana benthamiana) and X. citri subsp. citri on host orange (Citrus sinensis), confirming bioactivity of L. crescens LPS in activation of systemic acquired resistance (SAR). L. crescens LPS elicited a rapid burst of nitric oxide (NO) in suspension cultured tobacco cells. Pharmacological inhibitor assays confirmed that arginine-utilizing NO synthase (NOS) activity was the primary source of NO generation elicited by L. crescens LPS. LPS treatment also resulted in biological markers of NO-mediated SAR activation, including an increase in the glutathione pool, callose deposition, and activation of the salicylic acid and azelaic acid (AzA) signaling networks. Transient expression of ‘Ca. L. asiaticus’ bacterioferritin comigratory protein (BCP) peroxiredoxin in tobacco compromised AzA signaling, a prerequisite for LPS-triggered SAR. Western blot analyses revealed that ‘Ca. L. asiaticus’ BCP peroxiredoxin prevented peroxynitrite-mediated tyrosine nitration in tobacco. ‘Ca. L. asiaticus’ BCP peroxiredoxin (i) attenuates NO-mediated SAR signaling and (ii) scavenges peroxynitrite radicals, which would facilitate repetitive cycles of ‘Ca. L. asiaticus’ acquisition and transmission by fecund psyllids throughout the limited flush period in citrus. [Formula: see text] Copyright © 2022 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license .

CANDIDATUS LIST No. 3. Lists of names of prokaryotic Candidatus taxa

Citation
Oren, Garrity (2022). International Journal of Systematic and Evolutionary Microbiology 72 (1)
Names (108)
“Anthektikosiphon” “Aminobacteroides” “Acidifodinimicrobium” “Abditibacter” “Undinarchaeaceae” “Thiobarbaceae” “Tepidaquicellaceae” “Nanohalobiaceae” “Nanogingivalaceae” “Magnetomoraceae” “Macinerneyibacteriaceae” “Hakubellaceae” “Fermentimicrarchaeaceae” “Chazhemtonibacteriaceae” “Aminobacteroidaceae” “Adiutricaceae” “Tepidaquicellales” “Nanohalobiales” “Nanogingivalales” “Naiadarchaeales” “Methylospongiales” “Macinerneyibacteriales” “Hakubellales” “Guanabaribacteriales” “Mycoplasma erythrocervae” “Methanoflorens crillii” “Mastigocoleus perforans” “Liberibacter brunswickensis” “Ischnodemia utriculi” “Halobeggiatoa borealis” “Forterrea multitransposorum” “Fibrimonas termitidis” “Finniella dimorpha” “Euplotella sexta” “Entotheonella gemina” “Fermentimicrarchaeales” “Desulfofervidales” “Adiutricales” “Endohaliclona renieramycinifaciens” “Ehrlichia shimanensis” “Ehrlichia regneryi” “Didemniditutus mandelae” “Desulfosporosinus infrequens” “Desulfopertinax cowenii” “Cytophaga massiliensis” “Cuticulibacterium kirbyi” “Clostridium timonense” “Clostridium massiliense” “Cibionibacter quicibialis” “Brocadia braziliensis” “Borrelia fainii” “Borrelia ivorensis” “Borrelia africana” “Bartonella rudakovii” “Bartonella negevensis” “Bartonella khokhlovae” “Bartonella gerbillinarum” “Undinarchaeia” “Syntrophaliphaticia” “Nanosyncoccia” “Nanoperiodontomorbia” “Nanohalobiia” “Macinerneyibacteriia” “Desulfofervidia” “Bandiella numerosa” “Azospirillum massiliense” “Arocatia carayonii” “Aramenus sulfurataquae” “Annandiella pinicola” “Annandiella adelgistsugae” “Anaerococcus timonensis” “Anaerococcus phoceensis” “Anaerococcus massiliensis” “Anadelfobacter sociabilis” “Acidiflorens stordalenmirensis” “Theodorhartigia” “Stammera” “Rubidus” “Roseilinea” “Reconciliibacillus” “Pleuronema” “Parafinniella” “Paracaedimonas” “Ozemibacter” “Nitrobium” “Neowolbachia” “Ischnodemia” “Forterrea” “Fibrimonas” “Euplotella” “Endohaliclona” “Didemniditutus” “Cuticulibacterium” “Cibionibacter” “Changshengia” “Arocatia” “Aramenus” “Annandiella” “Acidiflorens” “Ozemibacteraceae” “Fibrimonadaceae” “Ozemibacterales” “Methanoflorentales” “Fibrimonadales” “Caenarcanales” “Ozemibacteria” “Saccharimonadia” Elulimicrobiia
Subjects
Ecology, Evolution, Behavior and Systematics General Medicine Microbiology

Candidatus Thiovulum sp. strain imperiosus: the largest free-living Epsilonproteobacteraeota Thiovulum strain lives in a marine mangrove environment

Citation
Sylvestre et al. (2022). Canadian Journal of Microbiology 68 (1)
Names (1)
Ca. Thiovulum imperiosus
Subjects
Applied Microbiology and Biotechnology General Medicine Genetics Immunology Microbiology Molecular Biology
Abstract
A large (47.75 ± 3.56 µm in diameter) Thiovulum bacterial strain forming white veils is described from a marine mangrove ecosystem. High sulfide concentrations (up to 8 mM of H2S) were measured on sunken organic matter (wood/bone debris) under laboratory conditions. This sulfur-oxidizing bacterium colonized the organic matter, forming a white veil. According to conventional scanning electron microscope (SEM) observations, bacterial cells are ovoid and slightly motile by numerous small flagella present on the cell surface. Large intracytoplasmic internal sulfur granules were observed, suggesting a sulfidic-based metabolism. Observations were confirmed by elemental sulfur distribution detected by energy-dispersive X-ray spectroscopy (EDXS) analysis using an environmental scanning electron microscope (ESEM) on non-dehydrated samples. Phylogenetic analysis of the partial sequence of 16S rDNA obtained from purified fractions of this Epsilonproteobacteraeota strain indicates that this bacterium belongs to the Thiovulaceae cluster and could be one of the largest Thiovulum ever described. We propose to name this species Candidatus Thiovulum sp. strain imperiosus.