Citrus greening disease, recently known as huanglongbing disease, is known to wreak havoc not only in Nepal but across the globe as it is non-curable once trees are affected. In 1919, this disease was reported first time in China, most likely originating from Taiwan. It then spread to more than a hundred countries and was recorded in Nepal for the first time from Pokhara Valley in 1968. Till now, there is no established solution for this century-old and yet, newly evolving disease. Being a vector-borne bacterial disease, the use of antibiotics had been a practice on a large scale that had led to the development of resistance. This disease has been more challenging to the developing and least- developed countries like Nepal. Thus, this paper aims to solve the problems of all the farmers engaged in citriculture by making them aware of the best-integrated management approaches that would help them increase their productivity and ultimately contribute to food security and sustainability. Detailed information about the disease, together with various techniques for integrated management and control of this disease is in this review. Thus, this paper will help farmers, traders, and planners.