Allen, S. W.


Publications
1

Evidence for the Biosynthesis of Bryostatins by the Bacterial Symbiont “ Candidatus Endobugula sertula” of the Bryozoan Bugula neritina

Citation
Davidson et al. (2001). Applied and Environmental Microbiology 67 (10)
Names
“Endobugula sertula”
Abstract
ABSTRACT The marine bryozoan, Bugula neritina , is the source of the bryostatins, a family of macrocyclic lactones with anticancer activity. Bryostatins have long been suspected to be bacterial products. B. neritina harbors the uncultivated gamma proteobacterial symbiont “ Candidatus Endobugula sertula.” In this work several lines of evidence are presented that show that the symbiont is the most likely