Hogenhout, S. A.


The crystal structure of the malic enzyme fromCandidatusPhytoplasma reveals the minimal structural determinants for a malic enzyme

Alvarez et al. (2018). Acta Crystallographica Section D Structural Biology 74 (4)
Ca. Phytoplasma
Phytoplasmas are wall-less phytopathogenic bacteria that produce devastating effects in a wide variety of plants. Reductive evolution has shaped their genome, with the loss of many genes, limiting their metabolic capacities. Owing to the high concentration of C4compounds in plants, and the presence of malic enzyme (ME) in all phytoplasma genomes so far sequenced, the oxidative decarboxylation of L-malate might represent an adaptation to generate energy. Aster yellows witches'-broom (CandidatusPh