Welles, Laurens


Publications
4

Revealing the Metabolic Flexibility of “ Candidatus Accumulibacter phosphatis” through Redox Cofactor Analysis and Metabolic Network Modeling

Citation
Guedes da Silva et al. (2020). Applied and Environmental Microbiology 86 (24)
Names
“Accumulibacter phosphatis”
Abstract
Here, we demonstrate how microbial storage metabolism can adjust to a wide range of environmental conditions. Such flexibility generates a selective advantage under fluctuating environmental conditions. It can also explain the different observations reported in PAO literature, including the capacity of “ Ca . Accumulibacter phosphatis” to act like glycogen-accumulating organisms (GAOs). These observations stem from slightly different experimental conditions,

Revealing metabolic flexibility ofCandidatusAccumulibacter phosphatis through redox cofactor analysis and metabolic network modeling

Citation
da Silva et al. (2018).
Names
“Accumulibacter phosphatis”
Abstract
ABSTRACTEnvironmental fluctuations in the availability of nutrients lead to intricate metabolic strategies.CandidatusAccumulibacter phosphatis, a polyphosphate accumulating organism (PAO) responsible for enhanced biological phosphorus removal (EBPR) from wastewater treatment systems, is prevalent in aerobic/anaerobic environments. While the overall metabolic traits of these bacteria are well described, the inexistence of isolates has led to controversial conclusions on the metabolic pathways use