Papaleo, Stella


Publications
1

Unraveling and quantifying “CandidatusSaccharibacteria”:in silicoand experimental evaluation of V3-V4 16S rRNA metagenomics and qPCR protocols

Citation
Papaleo et al. (2024).
Names
Ca. Saccharibacteria
Abstract
AbstractBackgroundCandidate Phyla Radiation (CPR) is a large monophyletic group thought to cover about 25% of bacterial diversity. Due to peculiar characteristics and unusual 16S rRNA gene structure, they are often under-represented or lost in 16S rRNA-based microbiota surveys. Among CPR, “CandidatusSaccharibacteria” is a phylum experimentally found to modulate the immune response and enriched in the oral microbiota of subjects suffering from several immune-mediated disorders, e.g. food allergie