McPhail, Kerry L.


Publications
1

Increased Biosynthetic Gene Dosage in a Genome-Reduced Defensive Bacterial Symbiont

Citation
Lopera et al. (2017). mSystems 2 (6)
Names
“Didemniditutus” “Didemniditutus mandelae”
Abstract
Secondary metabolites, which are small-molecule organic compounds produced by living organisms, provide or inspire drugs for many different diseases. These natural products have evolved over millions of years to provide a survival benefit to the producing organism and often display potent biological activity with important therapeutic applications. For instance, defensive compounds in the environment may be cytotoxic to eukaryotic cells, a property exploitable for cancer treatment. Here, we desc